Fig. 5

Network meta-analysis results based on the cox proportional hazards model for OS and PFS. BSC, Best Supportive Care; N, number of patients; HR, Hazards ratios; OS, Overall Survival; PFS, Progression-free survival; RCT, Randomized Controlled Trial; REDo, regorafenib dose optimization; TAS-102, trifluridine/tipiracil; TAS-BEV, TAS-102 with bevacizumab