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Table 3 Identification of cost drivers

From: Cost of hemophilia A in Brazil: a microcosting study

Variable

Sub-groups

Cost per patient (R$)a

n (%)

p

Blood center

1

504,513 (326,200–853,159)

28 (20.0)

0.289

2

364,922 (197,522–698,929)

60 (42.9)

3

500,084 (179,742–940,828)

52 (37.1)

Age (years)

≤ 12

299,320 (157,536 − 503,463)

53 (37.9)

< 0.001

12–18

521,936 (338,050–690,006)

29 (20.7)

≥ 19

718,969 (226,939- 1,007,211)

58 (41.4)

Severity

Moderate

172,720 (96,264–278,445)

6 (4.3)

0.096

Severe

488,947 (239,520–805,822)

134 (95.7)

Inhibitors

No

440,752 (224,758 − 748,379)

120 (85.7)

0.175

Yes

702,444 (202,677–1,055,373)

20 (14.3)

Bleeding

No

446,173 (256,039–707,851)

79 (56.4)

0.764

Yes

455,488 (204,485–974,735)

61 (43.6)

Surgery

No

445,145 (217,936 − 773,504)

138 (98.6)

0.261

Yes

1,053,913 (767,551–1,340,276)

2 (1.4)

Hospitalization

No

446,173 (230,801 − 733,936)

131 (93.6)

0.625

Yes

873,538 (93,474–1,206,184)

9 (6.4)

ICU hospitalization

No

450,831 (222,116–773,504)

138 (98.6)

0.752

Yes

475,584 (276,607–674,561)

2 (1.4)

  1. aCost shown as median (IQR). n: number of patients; ICU: intensive care unit