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Table 1 Sample characteristics classified by age

From: Cost of hemophilia A in Brazil: a microcosting study

 

0–11 years

(n = 53)

12–18 years

(n = 29)

19 + years

(n = 58)

Total

(n = 140)

Age (years)a

6.07 ± 3.26

15.07 ± 2.20

33.62 ± 10.54

20.71 ± 15.64

Age at diagnosis (years)a

0.83 ± 1.49

1.79 ± 2.66

10.79 ± 11.49

5.16 ± 8.92

Severity of hemophilia A

  

Moderate

4%

3%

5%

4%

Severe

96%

97%

95%

96%

Presence of inhibitors

23%

7%

10%

14%

Presence of bone-joint conditions

19%

34%

69%

43%

Number of target joints affectedb

   

One

60%

30%

5%

18%

Two

30%

30%

18%

22%

Three

10%

40%

31%

28%

More than three

0%

0%

49%

32%

Patients with bleeding registered during the last year

43%

34%

48%

44%

Type of prophylaxisc

    

Primary continuous

45%

21%

0%

22%

Secondary continuous

21%

31%

12%

19%

Tertiary continuous

17%

31%

74%

44%

Intermittent

0%

7%

3%

3%

Consumption of FVIII (IU/kg/year/patient)a

3,702 (3,135)

3,182 (2,515)

4,274 (4,140)

3,819 (3,489)

  1. amean±SD.b Percentages referring to the total number of patients with bone-joint conditions. cDefined as Rayment et al., 2020 [16]