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Table 2 Cost data and methodology

From: Cost of illness of breast cancer in low- and middle-income countries: a systematic review

Author

Year

Country

Cost data duration

Sensiti-vity analysis

Discount rate

Perspective

Cost method

Cost unit

Direct medical costs*

Direct non-medical costs*

Indirect costs*

Pakseresht et al. [21]

2011

India

6 months

None

None

Societal

Bottom-up

Cost per patient

515

(0–3436)

619

(0–3093)

NA

Lan et al. [27]

2013

Vietnam

5 years

Yes

3%

Payer

Bottom-up

Annual cost per patient

809

(SD 605)

NA

NA

O’Neill et al. [20]

2015

Haiti

Treatment cycle

None

None

Societal

Bottom-up

Out-of-pocket cost per patient per treatment cycle

195

(171–297)

676

(502–974)

NA

Shankar et al. [22]

2018

India

Treatment cycle

None

None

Payer

Mixed

Cost per patient per treatment cycle

825

(172–858)

NA

NA

Mahmood et al. [26]

2018

Pakistan

Treatment cycle

None

None

Payer

Mixed

Cost per patient per treatment cycle

1534

(SD 1536)

378

(SD 365)

332

(SD 631)

Afkar et al. [24]

2020

Iran

Treatment cycle

None

3%

Payer

Bottom-up

Cost per patient per treatment cycle

4808**

NA

NA

Afkar et al. [23]

2021

Iran

One year

(private hospital)

Yes

None

Societal

Bottom-up

Annual cost per patient in private hospital

11,866

(SD 23,000)

201

(SD 827)

2208

(SD 5821)

One year

(public hospital)

as above

as above

as above

as above

Annual cost per patient in public hospital

4676

(SD 8005)

401

(SD 1063)

26,390

(SD 21,997)

Rezende et al. [17]

2021

Brazil

Annual cost

None

None

Payer

Top-down

Cost for country (2015–2017) (Brazil)

377 million**

NA

NA

Zheng et al. [18]

2022

China

Treatment cycle

None

None

Payer

Top-down

Annual BC cost for city (Dalian, China)

78 million**

NA

NA

Zhao et al. [19]

2022

China

Treatment

None

None

Payer

Top-down

Cost per patient per treatment

952

(708–1303)

NA

NA

Jalali et al. [25]

2023

Iran

Treatment cycle

None

None

Payer

Bottom-up

Cost per patient

9060

(SD 6761)

2233

(SD 2108)

1525

(SD 3152)

Umo et al. [28]

2023

Papua New Guinea

Treatment cycle

None

None

Payer

Bottom-up

Cost per patient

7248**

NA

NA

  1. *Total cost was reported as medians with ranges or means with standard deviation (SD) per patient unless specified
  2. Costs were stated in USD for 2022 based on CCEMG – EPPI-Centre Cost Converter; Costs rounded to the nearest whole numbers
  3. NA, not applicable; SD, standard deviation
  4. ** Cost range or SD was not reported in original study