Table 10 Patient management within the Radium-223 therapy in the INMM

before starting Radium-223 therapy

patient contacts (mobile phone, e-mail)

contacts to the referring/collaborating physician, and/or the GP

verifying the patient’s clinical status and laboratory parameters

instructions and informed consent (+  1 copy for the patient)

the schedule of the Radium-223 application dates and the dates when the results of the differential blood count are to be reported (for the physician and for the patient)

for the patient - contact to the INMM physician

before ordering the respective Radium-223 dose

differential blood count check - the results to be delivered to the INMM (10 days before the application)

checking the clinical status of the patient

ordering the Radium-223 dose for the patient (produced in Norway)

on the day of Radium-223 application

admission of the patient at the INMM reception desk

taking the patient’s anamnesis and his/her objective examination

insertion of an intravenous cannula for Radium-223 application

application of the respective dose of Radium-223, flushing with 0.9% sodium chloride before and after the application

30 min after the application - measuring of the patient’s dose rate

discharging the patient from the department approximately 60 min after admission

for the patient after each application: medical report - Radium-223 treatment protocol, and Statement on radioactive substance application

for the referring physician after each application: medical report - Radium-223 treatment protocol